ADSL and infection: The human bloodstream is a highly protected niche, and so to establish an infection in this environment the bacteria must evade many aspects of host immunity, such as the bacterial membrane damaging AMPs and HDFAs found in serum (Levy, 2000; Kenny et al., 2009; Beavers et al., 2019; Peschel et al., 1999; Ernst and Peschel, 2011; Joo and Otto, 2015; Kohler et al., 2009).