ARMS2 and age-related macular degeneration: Genotyping for single-nucleotide polymorphisms associated with AMD was performed on these cells and demonstrated heterozygosity for the risk allele in both ARMS2 (rs10490924: G;T; Rivera et al., 2005) and CFH (rs1061170: C;T; Despriet et al., 2006), both resulting in an elevated risk of AMD of 2.5×.