DUXAP9 and cancer: Ubiquitination of proteins is required for their proteasomal degradation and plays an important role in the progression of cancer.[23] Immunoprecipitation of EZH2 followed by antiubiquitin immunoblotting demonstrated that ubiquitinated EZH2 was markedly increased in SS‐DUXAP9‐transfected cells, whereas EZH2 ubiquitination was significantly decreased in DUXAP9‐overexpressing cells (Figure 7G–I).