Greater changes in NT‐proBNP associated with an increased risk of subsequent hospitalization for HF (N = 34; HR: 1.73 [95% CI: 1.03–2.90], p = .04 and all‐cause death (N = 42; HR: 1.71 [95% CI: 1.05–2.77], p = .03) in the fully adjusted model. This evidence concerns the gene NPPB and hydrops fetalis.