In NIDCM patients, the independent risk factors were gender (OR 2.329, 95% CI 1.521–3.566, P < 0.001), PAD (OR 20.935, 95% CI 1.829–239.580, P = 0.014), NT-proBNP (OR 2.620, 95% CI 2.169–3.164, P < 0.001) and eGFR (OR 1.885, 95% CI 1.498–2.372, P < 0.001). The gene discussed is NPPB; the disease is peripheral arterial disease.