A diagnosis of hyperlipidemia and statin treatment did not affect plasma apoE levels (Mann–Whitney U-test, p = 0.922) even when accounting for race/ethnicity (B/AA: Mann–Whitney U-test, p = 0.928, NHW: Student’s t-test, p = 0.849), and APOE genotype. Here, APOE is linked to hyperlipidemia.