Black/African Americans are significantly underrepresented in AD research and the limitations of our study in addition to the overall low sample size, include the low number of APOE ε2 and APOE ε4-carries in both racial/ethnic groups, the rather low number of APOE ε4 homozygotes and the complete absence of homozygous APOE ε2/ε2 individuals. The gene discussed is APOE; the disease is Alzheimer disease.