TERT and glioma: For example, the presence of the variant on the 17p13 locus in the tumour suppressor gene TP53 (tumour protein p53) [9], important in maintaining cellular homeostasis [10], as well as variants of telomerase reverse transcriptase (TERT) [11] - important for the telomer maintenance and cell immortalization, a long non-coding RNA CCDC26 - modulator of differentiation and death, and the tumour suppressors cyclin-dependent kinase inhibitors 2A and 2B (CDKN2A and CDKN2B) [12], which regulate cell cycle progress, correlate with higher glioma incidence.