Associations of genetically mimicked ASGR1 inhibitors with apoB [32], TG [20], apoA1 [32], HDL-cholesterol [20], total cholesterol [20], CAD [33], haemoglobin [34], haematocrit [34], red blood cell count [34], reticulocyte count [35], CRP [36], but not HbA1c [37] were replicated in different GWAS of European ancestry, and associations with liver function (ALP, AST, GGT and albumin) [38] and calcium [38] were replicated in GWAS of East Asians (Additional file 1: Supplemental Table S8). The gene discussed is APOB; the disease is coronary artery disorder.