TM6SF2 and Insulin resistance: The present study of patients with non-genotype 3 HCV infections showed that patients with the PNPLA3 rs738409 non-CC genotype had higher serum levels of TGs and insulin resistance than those with the CC genotype, and that the serum TGs, TC, and LDL-C levels were lower in patients with the TM6SF2 rs58542926 non-CC genotype than in those with the CC genotype.