First, further experiments (RNA interference or overexpression methods) are needed to investigate the specific molecular mechanisms of the identified ceRNA pairs in NSCLC progression in a hypoxic microenvironment, and the specific effects of the Wnt, Hippo, Rap1, calcium, mTOR, and TNF signaling pathways in NSCLC under hypoxic conditions should be further verified. This evidence concerns the gene MTOR and non-small cell lung carcinoma.