CD274 and neoplasm: In line with our previous observations, IFP-only transduced T cells with CTM + 12EC, CTM + 39EC, and CTM + 41EC constructs formed more conjugates with PD-L1+ than with WT tumour cells, whereas PTM, CTM, and CTMΔ12EC constructs did not engage tumour cells in the absence of the CAR (Fig. 3b).