In line with our previous observations, IFP-only transduced T cells with CTM + 12EC, CTM + 39EC, and CTM + 41EC constructs formed more conjugates with PD-L1+ than with WT tumour cells, whereas PTM, CTM, and CTMΔ12EC constructs did not engage tumour cells in the absence of the CAR (Fig. 3b). This evidence concerns the gene HSF4 and neoplasm.