Furthermore, on day five after ACT, while none of the mice treated with CAR T cells displayed a tumour signal (Fig. 4d), IFN-γ levels in the serum spiked in all mice within the CAR and CTM + 12EC group, as a functional corroboration of the observed clinical phenotype in these mice (Fig. 4e). The gene discussed is IFNG; the disease is neoplasm.