TGFB1 and osteoarthritis: The effectiveness of cell therapy for osteoarthritis yet has not been conclusively researched, but the secretion of anti-scarring factors (KGF, SDF1, MIP1a, MIP1b), anti-apoptosis factors (STC-1, SFRP2, TGF-β1, HGF), angiogenic factors (VEGF), and mitogenic Factors (TGF-α, TGF-β, HGF, IGF-1, FGF-2, EGF) can explain the associated natural repair mechanisms [85].