RUNX3 and cancer: To explore the major roles of RUNX3 in cancer, we generated stably transduced doxycycline (Dox)-inducible Tet-On expression of RUNX3 in the cervical cancer cell line HeLa (henceforth designated as HeLa-RUNX3) and performed transcriptomic profiling of HeLa-RUNX3 in the presence or absence of doxycycline.