To assess whether 10 DRG, age, gender, TNM stage, and AFP were independent prognostic factors for HCC patients, our forest plot results obtained by univariate and multivariate COX regression analysis showed that both T stage and SLC7A11 and LRPPRC were independent prognostic factors for patients with HCC (P<0.05) (Figure 2A). The gene discussed is LRPPRC; the disease is hepatocellular carcinoma.