SLC7A11 and hepatocellular carcinoma: Additionally, the study found that SLC7A11 gene is usually elevated in HCC tissues, and is associated with a worse prognosis of hepatocellular carcinoma patients, and artificial damage to SLC7A11 inhibit the growth and appreciation of hepatocellular carcinoma cells, and SLC7A11 dysfunction has also been shown to increase the intracellular reactive oxygen species level, which in turn leads to autophagic cell death in hepatocellular carcinoma cells [32, 33].