TTR and AL amyloidosis: More specific diagnostic imaging includes scintigraphy with bone-avid technetium (99mTc) markers like DPD (“bone scan”)18 or PET with specific markers originally developed for Alzheimer’s disease.19 DPD scintigraphy, either planar or with SPECT technique, and scored visually from 0-3 grades of myocardial uptake, detects ATTR, but is unreliable for AL amyloidosis.20 AL amyloidosis can be identified from serum and urine protein determination.