MAPK14 is a member of the MAP kinase family and is involved in a wide variety of cellular processes such as proliferation, differentiation, and transcription regulation, which can be activated by exposure to many types of cellular stress, among which, they were strongly respond to endotoxin, proinflammatory cytokines, TNF-a, and is a good predictor for sepsis (43). This evidence concerns the gene MAPK14 and Sepsis.