CD8A and myeloid sarcoma: An association between EBV and MS was hypothesized based on several factors, such as higher seropositivity against EBV among MS patients (19–21); higher presence of EBV in MS brain (19, 22, 23); an increase in EBV-specific CD8+ cells during MS relapses (19); and EBV-specific oligoclonal bands in MS CSF (24).