SOD1 and brain infarction: For example, EA at GV 20 and GV14 can significantly reduce the content of nitric oxide (NO), malondialdehyde (MDA), and NO synthase (NOS) activity, improve the activities of SOD and glutathione peroxidase (GSH-Px) regulate the production and clearance of free radicals in rats with cerebral infarction, and improve learning and memory abilities (Wang et al., 2004).