For example, MA at Tanzhong (CV17), Zhongwan (CV12), Qihai (CV6), Zusanli (ST36) and Xuehai (SP10) can reduce the number of apoptotic cells and the expression of proapoptotic Bax gene, increase the expression of anti-apoptotic gene B-cell lymphoma 2 (Bcl-2) in the CA1 region of the hippocampus, improve memory impairment caused by multiple cerebral infarction (Wang et al., 2009). The gene discussed is BCL2; the disease is memory.