In our study, genes of TPRGRS were identified to be associated with prognosis in GBM, namely MDK, NBEAL1, HOXA2, HOXA7, MTRF1L, EREG, EN1, HOXA5, SLC37A3, LAP3, ERP29, AUTS2, HSPA5, SLC6A6, and ARMC10. The gene discussed is MDK; the disease is glioblastoma.