In our study, genes of TPRGRS were identified to be associated with prognosis in GBM, namely MDK, NBEAL1, HOXA2, HOXA7, MTRF1L, EREG, EN1, HOXA5, SLC37A3, LAP3, ERP29, AUTS2, HSPA5, SLC6A6, and ARMC10. This evidence concerns the gene EN1 and glioblastoma.