CUL2 and cervical carcinoma: To further demonstrate whether the effects of miR-154-5p on cervical cancer were influenced by CUL2, CUL2 was stably overexpressed in the background of the Lv-miR-154-5p-OE group, named Lv-CUL2-OE, and miR-154-5p-overexpressing SiHa cells transfected with an empty vector were considered the control group (Lv-CUL2-CO) (Fig. 8A).