Similarly, Artemisinin, obtained from Artemisia annua and well-known for its antimalarial effect, has been found effective in treating AD by inhibiting activation of NF-κB and NLRP3 inflammasome in 5-month-old APPswe/PS1dE9 transgenic mice (Shi et al., 2013). This evidence concerns the gene NFKB1 and Alzheimer disease.