DEF8 and pancreatic adenocarcinoma: A heat map of the 10 prognostic gene expression profiles in PAAD samples revealed that DEF8, RMND5B, CXXC1, ZMAT1, and U2AF1L4 were highly expressed in the low-risk group, while RTP4, ZNF185, PRKCI, SERTAD2 and SP110 were highly expressed in the high-risk group (Figure 3D).