As for 2022, the most prominent keywords mainly include Heparin Induced Thrombocytopenia (HIT), NF-κB, Inflammatory Bowel Disease (IBD), Hyperinflammation, Chronic Mucocutaneous Candidiasis (CMC), Antiphospholipid Antibodies (aPL), Neutrophil Extracellular Traps (NETs). The gene discussed is NFKB1; the disease is inflammatory bowel disease.