NFKBIA and focal segmental glomerulosclerosis: reported that exosomal super‐repressor IκBα ameliorated kidney ischemia‐reperfusion injury.[22] Through retrospective and prospective cohort studies using different independent groups of FSGS patients, we previously identified a positive correlation of plasma level of miR‐186‐5p with proteinuria level in FSGS patients.[23] However, whether and how circulating miR‐186‐5p causes renal dysfunction remains unknown.