In Ly6d-overexpressing cells, we found enrichment of TF-binding motifs related to steatosis, including those of retinoid X receptor alpha (Rxra)31, MLX-interacting protein (Mlxip)32, and sterol-regulatory element-binding transcription factor 1 (Srebf1)33 (Fig. 4D and Supplementary Fig. 2c). Here, SREBF1 is linked to steatosis.