APOE and Alzheimer disease: In the logistic regression models, the longitudinal AD panel could significantly discriminate AD cases from controls (OR = 1.38, p = 0.012, Supplementary Table 11), in a model adjusted for age, sex, granulocyte proportion and APOE. The obtained OR, reflecting a 38% increase in odds for AD for one standard deviation increase in the longitudinal panel score, was however modest when compared to APOEɛ4 allele carriage (OR = 13.85, p < 0.00001, Supplementary Table 11).