It was found that the concentrations of CXCL1, CXCL2, CXCL4, CXCL5, CXCL7, CXCL8, CXCL9, CXCL10, CXCL12, CXCL13 and CXCL14 in tumor drainage blood and peripheral blood were considerably higher than those in patients without recurrence, as well as the down-regulation of CXCL factors’ expression inhibited cell lines’ ability to migrate. Here, CXCL1 is linked to neoplasm.