For example, as to osteoarthritis, it was revealed by Caxaria et al. that CXCL6 stimulated inflammation via recruiting and activating immune cells and a therapeutic strategy to disrupt the capacity of CXCL6 to bind glycosaminoglycans for the aim of dispelling inflammatory reaction was proposed according to this discovery [68]. The gene discussed is CXCL6; the disease is osteoarthritis.