TRPA1 and lung adenocarcinoma: TRPA1 is the most abundant redox-sensitive TRP isoform in most cancer types [8], including invasive ductal breast carcinoma and lung adenocarcinoma, in which it supports H2O2-evoked intracellular Ca2+ oscillations and Ca2+-dependent recruitment of pro-survival and antiapoptotic pathways to prevent ROS-induced cancer cell death [9].