PHF6 and acute myeloid leukemia: Upon treatment with BAY11-7082 of three times in 10 days, the mice engrafted with PHF6 OE Kasumi-1 cells showed slight infiltration of human AML cells (Yellow arrows) in BM than that of mice engrafted with control cells (Fig. 6E and Supplementary Fig. 7D), indicating that BAY11-7082 could partially rescue the over-proliferation of PHF6 OE Kasumi-1 cells in vivo.