Indeed, it has been reported that RMST (a) is deregulated in a series of human cancers [14, 15], (b) exerts an anti-tumoral role in triple-negative breast cancer [17], (c) regulates neurogenesis [23], and (d) promotes neural apoptosis through interacting with the ribonucleoprotein K (hnRNPK) and through the indirect activation of p53/mir-107 signaling pathway [30]. The gene discussed is TP53; the disease is cancer.