The a’ and b’ pathways were significant in both models, with more adiposity predicting higher inflammatory protein levels (IL-6: β = .274, p < .001; CRP: β = .429, p < .001), and higher inflammatory protein levels predicting more depression symptoms (IL-6: β = .125, p < .001; CRP: β = .108, p = .023), respectively. This evidence concerns the gene CRP and depressive symptom measurement.