Mutations in Mic60 (mitofilin) has been identified in Alzheimers's disease [135] and Parkinson's disease [136], while mutations in Mic14 (CHCHD10) have also been reported in Alzheimers's disease [137] and Charcot-Marie-Tooth [138], highlighting the critical dependence of neurons of an appropriate IMM ultrastructure. Here, IMMT is linked to Parkinson disease.