Through Gene Ontology (GO) analysis of AML samples, the DEGs in the high-risk group (high DGKα expression) in AML were found to be primarily involved in phospholipid binding, DAG kinase activity, and NAD+ kinase activity and to promote phospholipid, DAG, and glycerophospholipid metabolic processes (Fig. S2A). Here, DGKA is linked to acute myeloid leukemia.