IL4 and interstitial lung disease: The logistic regression analysis showed mRSS [OR 1.138 (CI 95%: 1.023–1.266), p < 0.05] and IL-4 [OR 1.017 (CI 95%: 1–1.034), p < 0.05] as variables associated with ILD (fibrotic involvement ≥ 10% of lung parenchyma) in SSc patients (Table 3).