The level of DDIT4 expression correlated positively with the infiltration of CD4+ T cells (Cor = 0.081, p < 0.05), neutrophils (Cor = 0.097, p < 0.01), and dendritic cells (Cor = 0.102, p < 0.01) and negatively with tumor purity (Cor =  − 0.179, p < 0.001) (Fig. 8). Here, CD4 is linked to neoplasm.