ELAVL1 and kidney disorder: Importantly, the HuR inhibitor, KH3, inhibits tubular HuR generation and action and markedly attenuates IR-induced tubulointerstitial injury and fibrosis, further confirming a pro-injury role of elevated HuR, as a key mediator, in kidney disease and the therapeutic potential of inhibition of HuR for inhibition of tubulointerstitial fibrosis and the progression of AKI to CKD.