The immunohistochemical markers were positive for AFP, Glypican-3 (GLP3), SALL-like protein 4 (SALL4), PMS2, MSH6, MLH1, MSH2, P16, oestrogen receptor (ER), progesterone receptor (PR), Ki-67, P53, NapsinA, cytokeratin (CK), EMA, and CDX2 (caudal type homeobox 2) and were negative for octamer 4 (OCT-4) and CD30, which is consistent with endometrioid carcinoma and clear cell carcinoma with a yolk sac component (G2) (Fig. 1). The gene discussed is AFP; the disease is clear cell adenocarcinoma.