STING1 and neoplasm: LID + US also significantly increased the percentage of CD80 + DC in the tumor (Fig. 5g), increased the percentage of CD86 + DC in the tumor-draining lymph nodes (Fig. 5h), and enhanced the phosphorylation of TBK1 and IRF3, which were related to the activation of STING pathway in the tumor tissue (Fig. 5i).