UCHL1 and neoplasm: Recent evidence has verified the overexpression of UCH-L1 in many types of cancer including but not limited to acute lymphoblastic leukemia, non-small cell lung cancer, neuroblastoma, pancreatic, prostate, and medullary thyroid cancers.[11] It was also shown that UCH-L1 is a key regulator of tumor invasion and metastasis.[12]