MKI67 and lung adenocarcinoma: Several studies indicated that there was no correlation between the expression of ki-67 and EGFR mutation,[32] but some studies also found that patients in the low expression group of Ki-67 were more prone to EGFR gene mutation than those in the high expression group of ki-67.[33] Genetic analysis of lung adenocarcinoma pathways has shown that the cell cycle stimulation pathway is closely associated with prognosis and differentiation of lung adenocarcinoma subsets with increased solid components.