MKI67 and ocular melanoma: Gupta et al. [22] stated that the tested L. reuteri strains (LR) were effective in reducing OM severity, as it was found that the epithelial damage was less severe in the group injected with 5-FU and fed with LR in drinking water (5-FU/LR group) (p < 0.001) and had higher expression of Ki-67 protein (proliferation marker) in basal epithelial cells (p < 0.001) resulting in a higher epithelial regeneration, comparing to the 5-FU/water group.