JAK3 and rheumatoid arthritis: Study of Chen et al. (Chen et al. 2018) result is agreeing with the study result of the inhibitory effect TLA and TLA-encapsulated niosomes on JAK3 where Chen et al. noticed that Toxoplasma excreted-secreted antigens (ESA) inhibited JAK3 (Kumar et al. 2021) to which the targeted inhibitory medication tofacitinib is applied for RA treatment, confirming the anti-arthritic anti-inflammatory role of TLA.