4D-150 (4D Molecular Therapeutics) for wet AMD RGX-314 (REGENXBIO Inc.) uses AAV8 to encode for anti-VEGF Fab QPI-1007 siRNA (Quark Pharmaceuticals) for non-arteritic anterior ischemic optic neuropathy Tivanisiran (Sylentis) for ocular pain and dry eye disease. This evidence concerns the gene VEGFA and wet macular degeneration.