OAS1 and COVID-19: A higher expression of OAS1 may be characteristic of mild-moderate COVID-19 patients while the expression deficiency has been related to a higher risk of severe COVID-19 in other studies (Ziegler et al., 2021; Banday et al., 2022) suggesting a protective effect in SARS-CoV-2 infection for OAS1. This gene was the only one dysregulated between sexes with higher levels of expression among men.