In addition, clinical factors such as the presence of an underlying autoimmune disease16,77 and the nuclear expression of BCL10 or NF-kB were demonstrated to be significantly associated with independence of the lymphoma growth from H. pylori-mediated stimulation both in individuals with and without the t(11;18)(q21,q21) translocation.78, –80. Here, NFKB1 is linked to lymphoma.