For instance, AML-associated NUP98 fusion proteins were shown to recruit CREBBP/EP300 into condensates via interaction with FG repeat-containing IDRs to promote histone acetylation at promoters of protooncogenes.61 It would be, therefore, of interest to explore the effect of A-485 on condensates nucleated by different NUP98 fusion proteins. The gene discussed is EP300; the disease is acute myeloid leukemia.