Then, multiple immune fluorescence staining (MIF) of breast cancer tissue sections showed that the infiltration ratio of CD8+ T cells was positively closely related with the expression level of PTPRC (R=0.85, P=1.7e-05, Figures 11C, D), while there was no obvious relationship between CD8+ T cells and IKZF3 (R=0.24, P=0.35, Figures 11C, D). The gene discussed is IKZF3; the disease is breast cancer.