By comparing HIC1 expression between TCGA tumor samples and GTEx normal samples, upregulation of HIC1 was also detected in GBM, LAML, PAAD, and STAD, and downregulation of HIC1 was also found in ACC, ESCA, LGG, LIHC, OV, PRAD, SKCM, and UCS. This evidence concerns the gene HIC1 and neoplasm.