To further explore the relative roles of RORα cell-intrinsic expression in CD4 cells or ILC2 in the expulsion of worms after nematode infection, we used CreERT2 mice for tamoxifen-inducible Rora deficiency in CD4 cells (Rorafl/flCD4CreERT2) and ILC2s (Rorafl/flID2CreERT2). This evidence concerns the gene CD4 and Nematoda infectious disease.