However, there was no difference in the HDM-induced pulmonary inflammation between Rorafl/fl and Rorafl/flCD4Cre mice with comparable PAS score, BAL cell counts, eosinophilia, goblet cell hyperplasia, as well as levels of IL-4, IL-5, IL-17, and IFN-γ in lung tissue. The gene discussed is IL17A; the disease is Increased total eosinophil count.