vWF is found in plasma‐derived sEVs from atrial fibrillation patients.[25] In various types of cancers, including glioblastoma,[26] oral squamous cell carcinoma,[27] and chronic hepatitis‐related liver disease,[16, 28] vWF has been shown to be upregulated in circulating sEVs. This evidence concerns the gene VWF and oral cavity squamous cell carcinoma.